Publication 논문

2021

  1. Jeong GY, Park MK, Choi HJ, An HW, Park YU, Choi HJ, Park J, Kim HY, Son T, Lee H, Min KW, Oh YH, Lee JY, Kong G. (2021) NSD3-Induced Methylation of H3K36 Activates NOTCH Signaling to Drive Breast Tumor Initiation and Metastatic Progression. Cancer Res. 2021 Jan 1;81(1):77-90.

2019

  1. Hee-Joo Choi, Sora Jin, Hani Cho, Hee-Young Won, Hee Woon An, Ga-Young Jeong, Young-Un Park, Hyung-Yong Kim, Mi Kyung Park, Taekwon Son, Kyueng-Whan Min, Ki-Seok Jang, Young-Ha Oh, Jeong-Yeon Lee, and Gu Kong (2019) CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1-ErbB-PI3K signaling. EMBO rep. in press
  2. Kim HY, Choi HJ, Lee JY, Kong G (2019) Cancer Target Gene Screening: a web application for breast cancer target gene screening using multi-omics data analysis. Brief Bioinform. 2019 Jan 29.

2018

  1. Lee JY, Joo HS, Choi HJ, Jin S, Kim HY, Jeong GY, An HW, Park MK, Lee SE, Kim WS, Son T, Min KW, Oh YH, Kong G (2018) Role of MEL-18 amplification in anti-HER2 therapy of breast cancer. J NCI. 2018 Sep 27;111(6):609-619
  2. Choi HJ, Joo HS, Won HY, Min YW, Kim HY, Son T, Oh YH, Lee JY, Kong G (2018) Activation of ER and IGF1R-ErbB Signaling in RBP2-mediated Tamoxifen Resistance in Breast Cancer. Natl Cancer Inst. 2018 Apr 1;110(4).

2017

  1. Davies H, Morganella S, Purdie CA, Jang SJ, Borgen E, Russnes H, Glodzik D, Zou X, Viari A, Richardson AL, Børresen-Dale AL, Thompson A, Eyfjord JE, Kong G, Stratton MR, Nik-Zainal S.(2017) Whole-Genome Sequencing Reveals Breast Cancers with Mismatch Repair Deficiency. Cancer Res. 2017 Sep 15;77(18):4755-4762
  2. Lee JY, Park JH, Choi HJ, Won HY, Joo HS, Shin DH, Park MK, Han B, Kim KP, Lee TJ, Croce CM, Kong G (2017) LSD1 demethylates HIF1α to inhibit hydroxylation and ubiquitin-mediated degradation in tumor angiogenesis. Oncogene 2017 Sep 28;36(39):5512-5521.
  3. Kim HY, Choi JW, Lee JY, Kong G (2017) Gene-based comparative analysis of tools for estimating copy number alterations using whole-exome sequencing data. Oncotarget. 2017 Apr 18;8(16):27277-27285
  4. Davies H, Glodzik D, Morganella S, Yates LR, Staaf J, Zou X, Ramakrishna M, Martin S, Boyault S, Sieuwerts AM, Simpson PT, King TA, Raine K, Eyfjord JE, Kong G, Borg Å, Birney E, Stunnenberg HG, van de Vijver MJ, Børresen-Dale AL, Martens JW, Span PN, Lakhani SR, Vincent-Salomon A, Sotiriou C, Tutt A, Thompson AM, Van Laere S, Richardson AL, Viari A, Campbell PJ, Stratton MR, Nik-Zainal S. (2017) HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. Nat Med. 2017 Apr;23(4):517-525
  5. Glodzik D, Morganella S, Davies H, Simpson PT, Li Y, Zou X, Diez-Perez J, Staaf J, Alexandrov LB, Smid M, Brinkman AB, Rye IH, Russnes H, Raine K, Purdie CA, Lakhani SR, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL, Richardson AL, Kong G, Viari A, Easton D, Evan G, Campbell PJ, Stratton MR, Nik-Zainal S. (2017) A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat Genet. 2017 Mar;49(3):341-348

2016

  1. Lee JY, Kong G (2016) Roles and epigenetic regulation of epithelial-mesenchymal transition and its transcription factors in cancer initiation and progression. Cell Mol Life Sci. 2016 Dec;73(24):4643-4660
  2. Nik-Zainal S, Davies E,…., Richardson AL, Kong G*, Thomas G*, Stratton M* (2016) The somatic genetics of breast cancer revealed by 560 whole genome sequences. (*co-correspondence) Nature. 2016 May 2; 534(7605): 47-54.
  3. Morganella S Alexandrov BL, ….. Kong G, …. Thomas G, Stratton M, Nik-Zainal S (2016) The topography of mutational processes in breast cancer genomes. Nat Commun. 2016 May 2;7:11383.
  4. Kim T, Yoshida K, Kim YK, Tyndel MS, Park HJ, Choi SH, Ahn JS, Jung SH, Yang DH, Lee JJ, Kim HJ, Kong G, Ogawa S, Zhang Z, Kim HJ, Kim DD(2015) Clonal dynamics in a single AML case tracked for 9 years reveals the complexity of leukemia progression. Leukemia. 2016 Feb;30(2):295-302

2015

  1. Lee LY and Kong G (2015) DOT1L: a new therapeutic target for aggressive breast cancer. Oncotarget. 2015 Oct 13;6(31):30451-2.
  2. Choi HJ, Park JH, Park MK, Lee CH, Lee JY, Kong G (2015) UTX induces epigenetic silencing of CDH1 transcription factors by cooperating with LSD1 and HDAC1. EMBO reports, 2015 Oct;16(10):1288-98.
  3. George J, Lim JS, Jang SJ, Cun Y, Ozretic L, Kong G, Leenders F, Lu X, Fernández-Cuesta L, Bosco B et al. (2015) Comprehensive genomic profiles of small cell lung cancer. Nature. 2015 Aug 6; 524(7563):47-53.
  4. Cho MH, Park JH, Choi HJ, Park MK, Lee CH, Oh SH, Song YS, Kim HS, Oh YH, Lee JY, Kong G (2015) DOT1L cooperates with c-Myc/p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression. Nature Communications 2015 Jul 22; 6:7821(1-14)
  5. Lee LY and Kong G (2015) MEL-18, a tumor suppressor for aggressive breast cancer. Oncotarget 2015 Jun 30; 6(18):15710-1.
  6. Shin DH, Park JH, Lee JY, Won HY, Jang KS, Min KH, Jang SH, Woo JK, Oh SH, Kong G (2015) Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesis. Oncotarget 2015 Jul 10; 6(19):17276-90
  7. Lee JY, Won HY, Park JH, Kim HY, Choi HJ, Shin DH, Kang JH, Woo JK, Oh SH, Son T, Choi JW, Kim SH, Kim HY, Yi K, Jang KS, Oh YH, Kong G (2015) MEL-18 loss mediates estrogen receptor-α downregulation and hormone independence. J Clin Invest. 2015 May 1;125(5):1801-14

2014

  1. Choi S, Kim HR, Sung CO, Kim J, Kim S, Ahn SM, Choi CM, Chun SM, Choi EK, Kim SW, Kim YH, Lee JY, Song JS, Kim D, Haq F, Lee SY, Lee JE, Jung WR, Jang HY, Yang E, Lee C, Yu E, Kong G*, Baek D*, Jang SJ* (2014) Genomic Alterations in the RB Pathway Indicate Prognostic Outcomes of Early-Stage Lung Adenocarcinoma. Clin Cancer Res. 2015 Jun 1;21(11):2613-23.
  2. Kim HY, Park JH, Won HY, Lee JY, Kong G (2015) CBX7 inhibits breast tumorigenicity through DKK-1-mediated suppression of the Wnt/β-catenin pathway FASEB J 2015 Jan;29(1):300-13
  3. Ahn SM, Jang SJ, Shim JH, Kim D, Hong SM, Sung CO, Baek D, Haq F, Ansari AA, Lee SY, Chun SM, Choi S, Choi HJ, Kim J, Kim S, Hwang S, Lee YJ, Lee JE, Jung WR, Jang HY, Yang E, Sung WK, Lee NP, Mao M, Lee C, Zucman-Rossi J, Yu E, Lee HC, Kong G (2014) A genomic portrait of resectable hepatocellular carcinomas: Implications of RB1 and FGF19 aberrations for patient stratification. Hepatology 2014 Dec; 60(6):1972-82
  4. Genomic profile analysis of diffuse-type gastric cancers. (2014 ) Lee YS, Cho YS, Lee GK, Lee S, Kim YW, Jho S, Kim HM, Hong SH, Hwang JA, Kim SY, Hong D, Choi IJ, Kim BC, Kim BC, Kim CH, Choi H, Kim Y, Kim KW, Kong G, Kim HL, Bhak J, Lee SH, Lee JS. Genome Biology 2014 Apr 1;15(4):R55 :1-15
  5. Lee JY, Park MK, Park JH, Lee HJ, Shin DH, Kang Y, Lee CH, Kong G (2014) Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer. Oncogene. 2014 Mar 6; 33(10):1325-35.

Before 2013

  1. Kim RJ, Park JR, Roh KJ, Choi AR, Kim SR, Kim PH, Yu JH, Lee JW, Ahn SH, Gong G, Hwang JW, Kang KS, Kong G, Sheen YY, Nam JS (2013) High Aldehyde Dehydrogenase Activity Enhances Stem Cell Features in Breast Cancer Cells by Activating Hypoxia-Inducible Factor-2α Cancer Letter 2013 Jun 1;333(1):18-31
  2. Won HY, Lee JY, Shin DH, Park JH, Nam JS, Kim HC, Kong G (2012) Loss of Mel-18 enhances breast cancer stem cell activity and tumorigenicity through activating Notch signaling mediated by the Wnt/TCF pathway. FASEB J. 2012 Dec;26(12):5002-13
  3. Jung SK, Kim K, Tae K, Kong G, Kim MK (2012) The effect of raw vegetable and fruit intake on thyroid cancer risk among women: a case-control study in South Korea. Br J Nutr. 2012 Mar 28:1-11.
  4. Park JH, Lee JY, Shin DH, Jang KS, Kim HJ, Kong G (2011). Loss of Mel-18 induces tumor angiogenesis through enhancing the activity. and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway. Oncogene 2011 Nov 10;30(45):4578-89
  5. Shin DH, Jang SH, Kang HC, Kim HJ, Oh SH, Kong G (2011). Constitutive Overexpression of Id-1 in Mammary Glands of Transgenic Mice Results in Precocious and Increased Formation of Terminal End Buds, Enhanced Alveologenesis, Delayed Involution. J Cell Physiol. 2011 May;226(5):1340-52
  6. Shim JH, Shin JA, Jung JY, Choi KH, Choi ES, Cho NP, Kong G, Ryu MH, Chae JI, Cho SD.(2011) Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1. Eur J Cancer Prev. 2011 Mar;20(2):102-11
  7. Oh M, Lee JY, Shin DH, Park JH, Oian T, Kim HJ, Cho SD, Oh SH, Min YK, Kong G. (2011) The in vitro and in vivo anti-tumor effect of KO-202125, a sauristolactam derivative, as a novel epidermal growth factor receptor inhibitor in human breast cancer. Cancer Sci. 2011 Mar; 102(3):597-604.
  8. Park JR, Kim NJ,Lee YK, Kim SR, Roh KJ, Oh SH, Kong G, Kang KS, Nam JS (2011) Dysadherin can enhance tumorigenesis by conferring properties of stem-like cells to hepatocellular carcinoma cells. J Hepatol. 2011 Jan;54(1):122-31.
  9. Lee MH, Kim JW, Kim JH, Kang KS, Kong G, Lee MO Gene expression profiling of murine hepatic steatosis induced by tamoxifen.(2010) Toxicol Lett. 2010 Dec 15;199(3):416-24.
  10. Qian T, Lee JY, Park JH, Kim HJ, Kong G (2010). Id1 enhances RING1b E3 ubiquitin ligase activity through the Mel-18/Bmi-1 polycomb group complex. Oncogene 2010 Oct 28;29(43):5818-27
  11. Yun SH, Kim K, Nam SJ, Kong G, Kim MK. (2010) The association of carbohydrate intake, glycemic load, glycemic index, and selected rice foods with breast cancer risk: a case-control study in South Korea. Asia Pac J Clin Nutr. 2010;19(3):383-92
  12. Yang YJ, Hwang SH, Kim HJ, Nam SJ, Kong G, Kim MK. Dietary intake of nitrate relative to antioxidant vitamin in relation to breast cancer risk: a case-control study. Nutr Cancer. 2010 Jul;62(5):555-66.
  13. Yang YJ, Nam SJ, Kong G, Kim MK. (2010) A case-control study on seaweed consumption and the risk of breast cancer. Br J Nutr. 2010 May;103(9):1345-53.
  14. Choi KH, Kim HK, Kim JH, Choi ES, Shin JA, Lee SO, Chintharlapalli S, Safe S, Abdelrahim M, Kong G, Choi HS, Jung JY, Cho HT, Cho NP, Cho SD. (2010) The p38 MAPK pathway is critical for 5,5'-dibromodiindolylmethane-induced apoptosis to prevent oral squamous carcinoma cells. Eur J Cancer Prev. 2010 Mar;19(2):153-9.
  15. Leem DH, Choi KH, Han HS, Kim JH, Shin JA, Choi ES, Shim JH, Kong G, Min YK, Nam JS, Oh SH, Kim KA, Kwon KH, Cho NP, Cho SD. (2010) KO-202125, a sauristolactam derivate, induces apoptosis to prevent KB human oral squamous carcinoma cells through inhibition of cyclooxygenase-2 expression. Eur J Cancer Prev. 2010 Jan;19(1):23-30.
  16. Kim RJ, Kim SR, Roh KJ, Park SB, Park JR, Kang KS, Kong G, Tang B, Yang YA, Kohn EA, Wakefield LM, Nam JS (2010) Ras activation contributes to the maintenance and expansion of Sca-1(pos) cells in a mouse model of breast cancer. Cancer Lett. 2010 Jan 28;287(2):172-81
  17. Min HK, Kong G, Moon MH (2010) Quantitative Analysis of Urinary Phospholipids Found in Patients with Breast Cancer by Nanoflow Liquid Chromatography-Tandem Mass Spectrometry: II. Negative Ion Mode Analysis of Four Phospholipid Classes. Analytical and Bioanalytical Chemistry Anal Bioanal Chem. 2010 Feb;396(3):1273-80.
  18. Cho NP, Han HS, Leem DH, Choi IS, Jung JY, Kim HJ, Moon KS, Choi KH, Soh Y, Kong G, Cho SD.(2009) Sulforaphane enhances caspase-dependent apoptosis through inhibition of cyclooxygenase-2 expression in human oral squamous carcinoma cells and nude mouse xenograft model. Oral Oncol. 2009 Aug;45(8):654-60.
  19. Kim H, Min HK, Kong G, Moon MH (2009) Quantitative Analysis of Phosphatidylcholines and Phosphatidylethanolamines in Urine of Patients with Breast Cancer by Nanoflow Liquid Chromatography/Tandem Mass Spectrometry Analytical and Bioanalytical Chemistry 2009 Mar;393(6-7):1649-56.
  20. Yin HQ, Je YT, Kim M, Kim JH, Kong G, Kang KS, Kim HL, Yoon BI, Lee MO, Lee BH. (2009) Analysis of Hepatic Gene Expression during Fatty Liver Change due to Chronic Ethanol Administration in Mice Toxicology and Applied Pharmacology 2009 Mar 15;235(3):312-20
  21. Lee J-A, Kang M-B,Jang S-Y, Quan T, Kim H-J, Kim C-H, Kim Y, Kong G (2009) Id-1 Activates Akt-mediated Wnt Signaling and p27Kip1 Phosphorylation through PTEN Inhibition. Oncogene 2009 Feb 12;28(6):824-31.
  22. Woo HM, Kim KM, Choi MH, Jung BH, Lee J, Kong G, Nam SJ, Kim S, Bai SW, Chung BC. (2009) Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers. Clin Chim Acta. 2009 Feb;400(1-2):63-9
  23. Byun JA, Choi MH, Moon MH, Kong G, Chul Chung B.(2009) Serum polyamines in pre- and post-operative patients with breast cancer corrected by menopausal status. Cancer Lett. 2009 Jan 18;273(2):300-4.
  24. Choi YJ, Choi YL, Cho EY, Shin YK, Sung KW, Hwang YK, Lee SJ, Kong G, Lee JE, Kim JS, Kim JH, Yang JH, Nam SJ. (2009) Expression of Bmi-1 protein in tumor tissues is associated with favorable prognosis in breast cancer patients. Breast Cancer Res Treat. 2009 Jan;113(1):83-93
  25. Kim JH, Nam SJ, Kong G, Kim MY (2008) Dietary intake of soy protein and tofu in association with breast cancer risk based on a case-control study. Nutrition and Cancer, 2008;60(5):568-76
  26. Kim H, Chung H, Kim HJ, Lee JY, Oh MY, Kim Y, Kong G. (2008) Id-1 regulates Bcl-2 and Bax expression through p53 and NF-kappaB in MCF-7 breast cancer cells. Breast Cancer Res Treat. 2008 Nov;112(2):287-96
  27. Kwon SB, Park JS, Yi JY, Hwang JW, Kim M, Lee MO, Lee BH, Kim HL, Kim JH, Chung H, Kong G, Kang KS, Yoon BI. (2008) Time- and Dose-based Gene Expression Profiles Produced by a Bile-duct-damaging Chemical, 4,4""-methylene Dianiline, in Mouse Liver in an Acute Phase. Toxicol Pathol. 2008 Sep ;36(5):660-73
  28. Gene expression profiles of murine fatty liver induced by the administration of methotrexate. (2008) Lee MH, Hong I, Kim M, Lee BH, Kim JH, Kang KS, Kim HR, Yoon BI, Chung H, Kong G, Lee MO. Toxicology . 2008 Jul 10;249(1):75-84.
  29. Lee JY, Jang KS, Shin DH, Oh MY, Kim Y, Kong G (2008) Mel-18 Negatively Regulates INK4a/ARF-Independent Cell Cycle Progression via Akt Inactivation in Breast Cancer. Cancer Reseach, 2008 Jun 1;68(11):4201-9.
  30. Ahn E, Kim H, Chung BC, Kong G, Moon MH (2008) Quantitative Profiling of Phosphatidylcholine and Phosphatidylethanolamine in a Steatosis/Fibrosis Model of Rat Liver by Nanoflow Liquid Chromatography/Tandem Mass Spectrometry, J. Chromatography A. 2008 Jun 13;1194(1):96-102.
  31. Lee MH, Kim M, Lee BH, Kim JH, Kang KS, Kim HL, Yoon BI, Chung H, Kong G, Lee MO.(2008) Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver. Toxicol Appl Pharmacol. 2008 Feb 1;226(3):271-84
  32. Chung H, Jung YM, Shin DH, Lee JY, Oh MY, Kim HJ, Jang KS, Jeon SJ, Son KH, Kong G.(2008) Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell lines in vitro and in nude mice xenografts. Int J Cancer. 2008 Feb 15;122(4):816-22.
  33. Hong SA, Kim K, Nam SJ, Kong G, Kim MK.(2008) A case-control study on the dietary intake of mushrooms and breast cancer risk among Korean women. Int J Cancer. 2008 Feb 15;122(4):919-23
  34. Yin HQ, Kim M, Kim JH, Kong G, Kang KS, Kim HL, Yoon BI, Lee MO, Lee BH.(2007) Differential gene expression and lipid metabolism in fatty liver induced by acute ethanol treatment in mice. Toxicol Appl Pharmacol. 2007 Sep 15;223(3):225-33.
  35. Yoo YG, Na TY, Yang WK, Kim HJ, Lee IK, Kong G, Chung JH, Lee MO (2007) 6-Mercaptopurine, an activator of Nur77, enhances transcriptional activity of HIF-1alpha resulting in new vessel formation. Oncogene. 2007 May 31; 26(26):3823-34.
  36. Kim HJ, Chung H, Yoo YG, Kim H, Lee JY, Lee MO, Kong G.(2007) Inhibitor of DNA Binding 1 Activates Vascular Endothelial Growth Factor through Enhancing the Stability and Activity of Hypoxia-Inducible Factor-1{alpha}.Mol Cancer Res. 2007 Apr;5(4):321-9
  37. Lee MH, Hong I, Kim M, Lee BH, Kim JH, Kang KS, Kim HL, Yoon BI, Chung H, Kong G, Lee MO.(2007) Gene expression profiles of murine fatty liver induced by the administration of valproic acid. Toxicol Appl Pharmacol. 2007 Apr 1;220(1):45-59
  38. Kim HT, Kong G, Denardo D, Li Y, Uray I, Pal S, Mohsin S, Hilsenbeck SG, Bissonnette R, Lamph WW, Johnson K, Brown PH (2006). Identification of biomarkers modulated by the rexinoid LGD1069 (bexarotene) in human breast cells using oligonucleotide arrays. Cancer Res.66(24):12009-18.
  39. Chung H, Kim HJ, Jang KS, Kim M, Yang J, Kang KS, Kim HL, Yoon BI, Lee MO, Lee BH, Kim JH, Lee YS, Kong G (2006).Comprehensive analysis of differential gene expression profiles on D-galactosamine-induced acute mouse liver injury and regeneration. Toxicology. 227(1-2):136-44.
  40. Yin HQ, Kim M, Kim JH, Kong G, Lee MO, Kang KS, Yoon BI, Kim HL, Lee BH (2006). Hepatic gene expression profiling and lipid homeostasis in mice exposed to steatogenic drug, tetracycline. Toxicol Sci. 94(1):206-16.
  41. Chung H, Kim HJ, Jang KS, Kim M, Yang J, Kim JH, Lee YS, Kong G(2006) Comprehensive analysis of differential gene expression profiles on diclofenac-induced acute mouse liver injury and recovery. Toxicol Lett. 30;166(1):77-87
  42. Cho SH, Jung BH, Lee SH, Lee WY, Kong G, Chung BC (2006) Direct determination of nucleosides in the urine of patients with breast cancer using column-switching liquid chromatography-tandem mass spectrometry. Biomed Chromatogr Nov;20(11):1229-36.
  43. Joung KE, Min KN, An JY, Kim DK, Kong G, Sheen YY.(2006) Potent In vivo Anti-Breast Cancer Activity of IN-2001, a Novel Inhibitor of Histone Deacetylase, in MMTV/c-Neu Mice. Cancer Res 66(10):5394-402.
  44. Jang KS, Paik SS, Chung H, Oh YH, Kong G (2006) MTA1 overexpression correlates significantly with tumor grade and angiogenesis in human breast cancers. Cancer Sci.: 97(5):374-9.
  45. Chung H, Jung JY, Cho SD, Hong KA, Kim HJ, Shin DH, Kim H, Kim HO, Shin DH, Lee HW, Jeong NS, Kong G (2006) The antitumor effect of LJ-529, a novel agonist to A3 adenosine receptor, in both estrogen receptor–positive and estrogen receptor–negative human breast cancers. Mol Cancer Ther 5: 685-692
  46. Yoo YG, Kong G, Lee OK. (2006) Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1 protein by recruiting histone deacetylase 1 EMBO J 25(6):1231-41.
  47. Jang KS, Han HX, Paik SS, Brown PH, Kong G. (2006) Id-1 overexpression in invasive ductal carcinoma cells is significantly associated with intratumoral microvessel density in ER-negative/node-positive breast cancer. Cancer Lett. 244(2):203-10
  48. Kong G, Kim HT, Wu K, DeNardo D, Hilsenbeck S, Xu XC, Lamph WW, Bissonnette R, Dannenberg AJ, Brown PH (2005) The RXR-Selective Retinoid, LGD1069, Down-regulates COX-2 Expression in Human Breast Cells by Transcription Factor Crosstalk. Cancer research 65(8):3462-9
  49. Chung H, Hong D, Kim HJ, Jang KS, Shin DM, Ahn JI, Lee YS, Kong G (2005) Differential gene expression profiles in the steatosis/fibrosis model of rat liver by chronic administration of carbon tetrachloride. Toxicology and Applied Pharmacology 208(3):242-54.
  50. Chun T, Rho SB, Byun HJ, Lee JY, Kong G (2005). The polycomb group gene product Mel-18 interacts with cyclin D2 and modulates its activity. FEBS Lett. 579(24):5275-80.
  51. Ahn NS, Hu H, Park JS, Park JS, Kim JK, An S, Kong G, Lee YS, Aruoma AI, Kang KS ( 2005 ) Molecular mechanisms of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced inverted-U shaped-dose responsiveness in anchorage independent growth and cell proliferation in human breast epithelial cells with stem cell characteristics. Mutation Research 579(1-2):189-99
  52. Chung H, Hong D, Kim HJ, Jang KS, Sheen YY, Ahn JI, Lee YS, Kong G ( 2005 ) Comprehensive analysis of differential gene expression profiles on carbon tetrachloride-induced rat liver injury and regeneration. Toxicology and Applied Pharmacology 206(1):27-42 2005
  53. Lee EJ, Kong G, Lee SH, Rho SB, Park CS, Kim BG, Bae DS, Kavanagh JJ, Lee JH (2005) Profiling of differentially expressed genes in human uterine leiomyomas. Int J Gynecol Cancer. 15(1):146-54
  54. Park JS, Noh DY, Kim SH, Kim SH, Kong G, Chang CC, Lee YS, Trosko JE, Kang KS (2004) Gene expression analysis in SV40-immortalized human breast luminal epithelial cells with stem cell characteristics using a cDNA microarray. Int J Oncol. 24(6):1545-58
  55. Lee KT, Lee YW, Lee JK, Choi SH, Rhee JC, Paik SS, Kong G (2004) Overexpression of Id-1 is significantly associated with tumor angiogenesis in human pancreas cancers. Br J Cancer 90(6):1198-203
  56. Chang YS, Kong G, Sun S, Liu D, El-Naggar AK, Khuri FR, Hong WK, Lee HY(2002) Clinical significance of insulin-like growth factor-binding protein-3 expression in stage I non-small cell lung cancer. Clin Cancer Res 8(12):3796-802
  57. Kong G, Chua SS, Yijun Y, Kittrell F, Moraes RC, Medina D Said, TK (2002) Functional analysis of cyclin D2 and p27Kip1 in cyclin D2 transgenic mouse mammary gland during development. Oncogene 21; 7214-7225
  58. Kong G, Kim EK, Kim WS, Lee KT, Lee YW, Lee JK, Paik SW, Rhee JC(2002) Cyclooxygenase-2 and inducible nitric oxide synthase in pancreatic cancer. J Gastro Hepa 17:914-921
  59. Kong G, Kim EK, Kim WS, Lee YW, Lee JK, Paik SW, Rhee JC, Choi KW, Lee KT(2001) Inducible nitric oxide synthase(iNOS) immunoreactivity and its Relationship to cell proliferation, apoptosis, angiogenesis, clinicopathologic characteristics, and patient survival in pancreatic cancer. Int J Pancrea 29(3):133-140
  60. Kong G, Lee S, Kim KS (2001) Inhibition of rac1 reduces PDGF-induced reactive oxygen species and proliferation in vascular smooth muscle cells. J Korean Med Sci 16(6):712-8
  61. Koo SH, Ihm CH, Kwon KC, Park JW, Kim JM, Kong G(2001) Genetic alterations in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Cancer Genet Cytogenet 130(1):22-8
  62. Hong KM, Jang SJ, Kong G, Song KY, Park JG, Kim DJ, Chung JH, Lee JH, Paik MK, Chung HK.(2001) A novel tumor-associated mucin of gastrointestinal carcinoma. J Cancer Res Clin Oncol 127(9):551-8
  63. Kong G, Oga A, Park CK, Kawauchi S, Furuya T, Sasaki K.(2001) DNA sequence copy number aberrations associated with histological subtypes and DNA ploidy in gastric carcinoma. Jpn J Cancer Res 92(7):740-7
  64. Oga A, Kong G, Tae K, Lee Y, Sasaki K.(2001) Comparative genomic hybridization analysis reveals 3q gain resulting in genetic alteration in 3q in advanced oral squamous cell carcinoma. Cancer Genet Cytogenet 127(1):24-9
  65. Oga A, Kong G, Ishii Y, Izumi H, Park CY, Sasaki K.(2001) Preferential loss of 5q14-21 in intestinal-type gastric cancer with DNA aneuploidy. Cytometry 15;46(1):57-62
  66. Shin KY, Moon HS, Park HY, Lee TY, Woo YN, Kim HJ, Lee SJ, Kong G.(2000) Effects of tumor necrosis factor-alpha and interferon-gamma on expressions of matrix metalloproteinase-2 and -9 in human bladder cancer cells. Cancer Lett 159(2):127-34
  67. Choi BY, Kim HY, Lee KH, Cho YH, Kong G (1999) Clofilium, a potassium channel blocker, induces apotosis of human promyelocytic leukemia (HL-60) cellls via Bcl-2 insensitive activation of caspase-3. Cancer letters 147:85-93
  68. Keum JS, Kong G, Yang SC, Shin DH, Park SS, Lee JH, Lee JD (1999) Cyclin D1 overexpression is an indicator of poor prognosis in resectable non-small cell lung cancer. Br J Cancer 81:127-132
  69. Kong G, Lee SJ, Kim HJ, Surh YJ, Kim ND (1999) Induction of Granulocytic Differentiation in Acute Promyelocytic Leukemia Cells(HL-60) by 2-(Allylthio) Pyrazine. Cancer Letters 142:1-8
  70. Im HJ, Kong G, Lee H (1999) Expression of Wilms’ Tumor Gene (WT1) in Children with Acute Leukemia. Pediatr Hemato Oncol, 16:109-18
  71. Surh YJ, Hurh YJ, Kang JY, Lee E, Kong G, Lee SJ (1999) Resveratrol, an Antioxidant Present in Red Wine, Induces Apoptosis in Human Promyelocytic Leukemia (HL-60) Cells. Cancer Letters 136:1-10
  72. Kong G, Shin KY, Oh YH, Lee JJ, Park HY, Woo YN, Lee JD (1998) p53 and Bcl-2 overexpression in invasive bladder cancers. Acta Oncologica 37:715-720.
  73. Koh HY, Cho NP, Kong G, Lee JD, Yoon K (1998) p53 mutations and HPV DNA in oral squamous cell carcinoma: correlation with apoptosis. Br. J Cancer., 78(3):354-359.
  74. Shin KY, Kong G, Kim WS, Lee TY, Woo YN, and Lee JD (1997) Overexpression of cyclin D1 correlates with early recurrence in superficial bladder cancers. Br. J Cancer., 75: 1788-1792.